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<title>Samuel Jenness: News</title>
<link>https://samueljenness.org/news.html</link>
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<description>Samuel Jenness, PhD, Associate Professor of Epidemiology at Emory University. Infectious disease modeling, network science, and HIV/STI prevention research.</description>
<lastBuildDate>Wed, 30 Sep 2026 04:00:00 GMT</lastBuildDate>
<item>
  <title>New paper (Parker): Enhanced Screening and STI Diagnoses after PrEP Initiation</title>
  <link>https://samueljenness.org/news/2026-09-30-prep-sti-screening.html</link>
  <description><![CDATA[
<p>New paper led by Anna Parker in <em>Epidemiology</em>: <strong>Enhanced Screening and Bacterial Sexually Transmitted Infection Diagnoses after HIV Pre-Exposure Prophylaxis Initiation</strong>. A self-controlled case series compared gonorrhea and chlamydia diagnosis rates before and after PrEP initiation among 9,143 commercially insured US males in MarketScan claims (2016–2019). Diagnoses rose for gonorrhea (IRR 3.47, 95% CI 2.57–4.72) and chlamydia (IRR 3.59, 2.50–5.27), mostly at extragenital sites. Against a Bayesian model of increased screening with no change in infection risk, observed rates exceeded expectations by 8% to 14%, with intervals including no excess. Increased asymptomatic screening accounted for about 80% of the rise in each infection, suggesting screening, rather than risk compensation, may explain most of it.</p>
<p><img src="https://samueljenness.org/img/papers/2026-09-30-prep-sti-screening.jpg" alt="Directed acyclic graph in which external risk factors X point to PrEP use, incident STI, and testing; PrEP use and incident STI both point to testing; and incident STI and testing both point to diagnosis" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/42813720/">PubMed</a> · <a href="https://doi.org/10.1097/EDE.0000000000002052">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2026-09-30-prep-sti-screening.html</guid>
  <pubDate>Wed, 30 Sep 2026 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Chandra): PrEP Reinitiation as a Target for Reducing HIV Incidence</title>
  <link>https://samueljenness.org/news/2026-08-29-prep-reinitiation-boston.html</link>
  <description><![CDATA[
<p>New paper led by Christina Chandra in <em>Lancet Regional Health – Americas</em>: <strong>PrEP Reinitiation, Uptake, and Persistence as Targets for Reducing HIV Incidence and Racial and Ethnic Inequities among Men Who Have Sex with Men in Boston, USA: A Network Modeling Study</strong>. A network model of 100,000 cisgender men in Boston was parameterized with electronic health record data from 37,722 men (2012–2023) and calibrated to local surveillance. Over 10 years, doubling reinitiation averted 15.8% of infections (1,481; number needed to treat 40), versus 10.0% for doubling uptake and 5.6% for maximizing persistence; a fivefold increase averted 32.6% at the same number needed to treat. Equity-focused reinitiation among Black and Hispanic men produced the most favorable relative disparity patterns, though inequities remained.</p>
<p><img src="https://samueljenness.org/img/papers/2026-08-29-prep-reinitiation-boston.jpg" alt="Two heat maps over a grid of PrEP uptake and PrEP reinitiation multipliers, showing the percent of infections averted rising above 30% toward higher values of both levers while the number needed to treat stays near 35 to 40 across most of the grid" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/42701478/">PubMed</a> · <a href="https://doi.org/10.1016/j.lana.2026.101620">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2026-08-29-prep-reinitiation-boston.html</guid>
  <pubDate>Sat, 29 Aug 2026 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Chandra): Scaling Up Event-Driven PrEP among MSM</title>
  <link>https://samueljenness.org/news/2026-08-28-event-driven-prep.html</link>
  <description><![CDATA[
<p>New paper led by Christina Chandra in the <em>Journal of Acquired Immune Deficiency Syndromes</em>: <strong>Modeling the Potential Impact of Scaling Up Event-Driven PrEP among Gay, Bisexual, and Other Men Who Have Sex with Men</strong>. A network model simulated HIV transmission among 100,000 men who have sex with men in Atlanta over 10 years, adding event-driven PrEP on the 2-1-1 schedule. Against a baseline of daily PrEP only, raising event-driven initiation until overall PrEP use nearly doubled (28.5% versus 16.1%) averted 18.3% of infections. Extending eligibility to any sexually active man averted 15.8%. Targeting men who discontinued daily PrEP with low adherence yielded no population-level improvement, and raising initiation mattered more than improving adherence.</p>
<p><img src="https://samueljenness.org/img/papers/2026-08-28-event-driven-prep.jpg" alt="Schematic contrasting a daily oral PrEP user, assigned one of three static adherence classes, with a 2-1-1 event-driven PrEP user whose sex acts are covered according to which pills around the act were taken" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/42664952/">PubMed</a> · <a href="https://doi.org/10.1097/QAI.0000000000003934">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2026-08-28-event-driven-prep.html</guid>
  <pubDate>Fri, 28 Aug 2026 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Jenness): Evolving Drivers of PrEP Discontinuation among US MSM</title>
  <link>https://samueljenness.org/news/2026-08-06-prep-discontinuation-drivers.html</link>
  <description><![CDATA[
<p>New paper in <em>AIDS</em>: <strong>Evolving Drivers of Preexposure Prophylaxis Discontinuation among US MSM, 2018–2024</strong>. We pooled seven waves of the American Men's Internet Survey and analyzed 3,074 former PrEP users who reported reasons for stopping, estimating adjusted prevalence by year with g-computation. Altered sexual activity was the most common reason (55%), followed by side effects (31.6%) and financial or access barriers (29.4%). After adjustment, altered sexual activity rose from 46.2% in 2018 to 61.2% in 2024, while privacy and discrimination concerns doubled from 5.6% to 11.3%, the only reason with a significant linear trend. Latent class analysis identified three discontinuation profiles; being uninsured most strongly predicted financial discontinuation (aOR 4.31).</p>
<p><img src="https://samueljenness.org/img/papers/2026-08-06-prep-discontinuation-drivers.jpg" alt="UpSet plot of reasons for stopping PrEP, with set sizes largest for altered sexual activity (1,690), side effects (970), and financial or access barriers (904), and intersection bars showing 995 respondents reporting altered sexual activity alone" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/42558064/">PubMed</a> · <a href="https://doi.org/10.1097/QAD.0000000000004593">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2026-08-06-prep-discontinuation-drivers.html</guid>
  <pubDate>Thu, 06 Aug 2026 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Quesada): Isolation and Masking Guidance in Office Workplaces</title>
  <link>https://samueljenness.org/news/2026-07-28-workplace-isolation-masking.html</link>
  <description><![CDATA[
<p>New paper led by Maria Garcia Quesada in <em>Epidemics</em>: <strong>Modeling the Impact of Adherence to U.S. Isolation and Masking Guidance on SARS-CoV-2 Transmission in Office Workplaces in 2021–2022</strong>. A network model representing contacts in the home, office, and community was parameterized with CorporateMix contact data and calibrated to the COVID-19 epidemic in Georgia from January 2021 through August 2022. Workplace transmission accounted for a small fraction of total infections at the reference level of adherence to CDC isolation and masking guidance. Raising adherence among office workers alone had limited additional benefit, given low workplace contact intensity and hybrid work arrangements, whereas raising adherence across the broader population was more effective at reducing cases and deaths among office workers.</p>
<p><img src="https://samueljenness.org/img/papers/2026-07-28-workplace-isolation-masking.jpg" alt="Model structure showing progression from susceptible through exposed, pre-clinical, clinical, and subclinical infection, with symptom onset and testing triggering isolation and masking" /></p>
<p><a href="https://doi.org/10.1016/j.epidem.2026.100935">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2026-07-28-workplace-isolation-masking.html</guid>
  <pubDate>Tue, 28 Jul 2026 04:00:00 GMT</pubDate>
</item>
<item>
  <title>NME short course starts at SISMID 2026</title>
  <link>https://samueljenness.org/news/2026-07-20-sismid-nme-2026.html</link>
  <description><![CDATA[
<p>Our <strong>Network Modeling for Epidemics (NME)</strong> short course starts today at the Summer Institute in Statistics and Modeling in Infectious Diseases (SISMID) at Emory University. Taught with Steven Goodreau and Martina Morris, NME covers stochastic network models for infectious disease transmission dynamics using <a href="https://www.epimodel.org/">EpiModel</a>. NME-I: Foundations runs July 20–22 and introduces network model specification with TERGMs and epidemic simulation over dynamic networks. NME-II: Applications runs July 22–24 and extends to research-level model building with the EpiModel API, multi-layer networks, and parameterization from egocentric network data.</p>
<p><a href="https://epimodel.github.io/sismid">Course materials</a> · <a href="https://sismid.sph.emory.edu">SISMID</a></p>
]]></description>
  <category>teaching</category>
  <guid>https://samueljenness.org/news/2026-07-20-sismid-nme-2026.html</guid>
  <pubDate>Mon, 20 Jul 2026 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Le Guillou): Risks and Benefits of Low-Barrier HIV PrEP Access</title>
  <link>https://samueljenness.org/news/2026-07-17-low-barrier-prep.html</link>
  <description><![CDATA[
<p>New paper led by Adrien Le Guillou in the <em>Journal of Infectious Diseases</em>: <strong>Potential Risks and Benefits of Low-Barrier Access and Monitoring for HIV Preexposure Prophylaxis: A Modeling Study</strong>. A network model of HIV/STI transmission among gay, bisexual, and other men who have sex with men in Atlanta compared clinic-based PrEP against over-the-counter delivery with simplified initiation and reduced monitoring. A 50% increase in PrEP coverage averted 15.4% of HIV infections, but clinical risks rose alongside it, including renal impairment exposure and TDF/FTC resistance. Sensitivity analyses indicated that confirming HIV-negative status at initiation reduced resistance by more than 90% without reducing prevention benefits.</p>
<p><img src="https://samueljenness.org/img/papers/2026-07-17-low-barrier-prep.jpg" alt="Modeled antiretroviral resistance per 100 HIV infections across levels of added over-the-counter PrEP coverage and the share of initiators confirming HIV-negative status beforehand" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/42467629/">PubMed</a> · <a href="https://doi.org/10.1093/infdis/jiag369">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2026-07-17-low-barrier-prep.html</guid>
  <pubDate>Fri, 17 Jul 2026 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Onwubiko): Mental Health Integration in PrEP Programs</title>
  <link>https://samueljenness.org/news/2026-07-15-mental-health-prep-integration.html</link>
  <description><![CDATA[
<p>New paper led by Udodirim Onwubiko in <em>BMC Health Services Research</em>: <strong>Evaluating Mental Health Integration in PrEP Programs to Reduce HIV Incidence among US Gay and Bisexual Men: A Network Modeling Study</strong>. The study adapted a stochastic network model of HIV transmission among gay and bisexual men in a southeastern US metropolitan area, adding individual-level sexual stigma and mental health factors. Maximal improvement in depression diagnosis and treatment alone averted 12% of new infections over ten years in the model. Combining that care with expanded pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) coverage for all HIV-negative individuals in PrEP settings reduced incidence by up to 41%, a final-year rate of 0.52 per 100 person-years.</p>
<p><img src="https://samueljenness.org/img/papers/2026-07-15-mental-health-prep-integration.jpg" alt="Modeled HIV incidence rate in year 10 across depression care scenarios for five depression screening and treatment strategies" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/42458454/">PubMed</a> · <a href="https://doi.org/10.1186/s12913-026-15074-0">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2026-07-15-mental-health-prep-integration.html</guid>
  <pubDate>Wed, 15 Jul 2026 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Chen): Temporal Connectivity of Social Contact Networks in India</title>
  <link>https://samueljenness.org/news/2026-07-06-temporal-connectivity-india.html</link>
  <description><![CDATA[
<p>New paper led by Dehao Chen in <em>Epidemiology</em>: <strong>Temporal Connectivity of Social Contact Networks in Urban and Rural India</strong>. The study used empirical social contact data from rural and urban Tamil Nadu, India, to parameterize dynamic network models, simulate daily contact networks over one year, and compute forward-reachable paths, the proportion of the population reachable from an index person through direct or indirect connections. Reachability at 365 days stayed bounded at home (0.06% rural, 0.03% urban) but expanded elsewhere, reaching 12.55% at work in rural networks versus 26.72% in urban networks, and 40.54% versus 67.99% in locations other than home, school, and work. The models indicated substantial epidemic potential for acute respiratory transmission.</p>
<p><img src="https://samueljenness.org/img/papers/2026-07-06-temporal-connectivity-india.jpg" alt="Percentage of the population reachable over one year through home, school, work, and other contacts in rural and urban networks, by age group" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/42406882/">PubMed</a> · <a href="https://doi.org/10.1097/EDE.0000000000002019">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2026-07-06-temporal-connectivity-india.html</guid>
  <pubDate>Mon, 06 Jul 2026 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Gandhi): Casual Contact in Drug-Resistant TB Transmission</title>
  <link>https://samueljenness.org/news/2026-04-28-casual-contact-tb.html</link>
  <description><![CDATA[
<p>New paper led by Neel Gandhi in <em>American Journal of Respiratory and Critical Care Medicine</em>: <strong>Role of Casual Contact in Drug-Resistant Tuberculosis Transmission: A Molecular Epidemiology Study</strong>. The study applied universal whole genome sequencing to isolates from 251 of 305 persons diagnosed with second-line drug-resistant tuberculosis (TB) in metropolitan Durban, South Africa, from June 2018 to December 2022, pairing sequences with named contacts and GPS coordinates of homes, clinics, and community locations. Among the 141 participants (56%) who clustered genotypically, 69 (49%) were epidemiologically linked through casual contact, compared with 13 (9%) linked through close contact. Living within 1 km was associated with clustering (odds ratio 17.9), as were person-to-person links (odds ratio 5.38).</p>
<p><img src="https://samueljenness.org/img/papers/2026-04-28-casual-contact-tb.jpg" alt="Close contact, casual contact, and unlinked epidemiologic links among the 141 genotypically clustered participants" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/42089682/">PubMed</a> · <a href="https://doi.org/10.1093/ajrccm/aamag140">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2026-04-28-casual-contact-tb.html</guid>
  <pubDate>Tue, 28 Apr 2026 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Traeger): Long-Acting Injectable Cabotegravir PrEP in Practice</title>
  <link>https://samueljenness.org/news/2026-04-15-cab-la-prep.html</link>
  <description><![CDATA[
<p>New paper led by Michael Traeger in <em>JAIDS</em>: <strong>Long-Acting Injectable Cabotegravir HIV PrEP Uptake, Adherence, and Persistence in Two Large US Integrated Healthcare Systems</strong>. The study used electronic health records from Kaiser Permanente Northern California and Mid-Atlantic States covering adults who received oral or injectable HIV preexposure prophylaxis (PrEP) between December 2021 and June 2024. Among 23,311 PrEP users, 180 (0.8%) received long-acting cabotegravir (CAB-LA), of whom 23.9% had no documented prior PrEP use. CAB-LA users were more often Black (18.9% versus 10.2%) or Hispanic (34.4% versus 23.6%) than oral-PrEP-only users. Of 688 non-lead-in injections, 90.4% arrived within 8 weeks plus 7 days, and persistence was 87.9% at 6 months and 74.9% at 12 months.</p>
<p><img src="https://samueljenness.org/img/papers/2026-04-15-cab-la-prep.jpg" alt="Cumulative probability of persisting on long-acting injectable cabotegravir PrEP during the first year after initiation" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/42150757/">PubMed</a> · <a href="https://doi.org/10.1097/QAI.0000000000003889">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2026-04-15-cab-la-prep.html</guid>
  <pubDate>Wed, 15 Apr 2026 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Anderson): Predicting High One-Time Partnership Rate Among MSM</title>
  <link>https://samueljenness.org/news/2026-03-01-partnerships-msm.html</link>
  <description><![CDATA[
<p>New paper led by Emeli Anderson in <em>AIDS and Behavior</em>: <strong>Predictive Models to Identify Factors Associated with a High One-Time Sexual Partnership Rate among U.S. Men Who Have Sex with Men</strong>. The study fit negative binomial and penalized logistic models to counts of one-time partnerships reported in a web-based egocentric network survey of men who have sex with men (MSM) in the United States. Predictors of a high rate were consistent across models: numbers of main and casual partners, exchange sex, use of apps or the internet to meet men, and non-injection drug use. Logistic models treating 6 partners per year as the high-count cut point performed best.</p>
<p><img src="https://samueljenness.org/img/papers/2026-03-01-partnerships-msm.jpg" alt="Observed and predicted distributions of one-time partnership counts across four predictive models" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/41934601/">PubMed</a> · <a href="https://doi.org/10.1007/s10461-026-05107-4">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2026-03-01-partnerships-msm.html</guid>
  <pubDate>Sun, 01 Mar 2026 05:00:00 GMT</pubDate>
</item>
<item>
  <title>New Merck-funded study on monthly HIV PrEP</title>
  <link>https://samueljenness.org/news/2026-02-01-monthly-prep.html</link>
  <description><![CDATA[
<p>New industry-funded study supported by <em>Merck &amp; Co.</em>, running through 2027: <strong>Monthly HIV Pre-Exposure Prophylaxis Preferences among U.S. Men Who Have Sex with Men</strong>. Pre-exposure prophylaxis (PrEP) is currently delivered either as a daily oral regimen or as a long-acting injectable given every two months, so a monthly formulation would sit between the two on dosing burden. The study measures how gay, bisexual, and other men who have sex with men weigh a monthly option against the formulations already available, then uses those preference estimates to parameterize a network transmission model. The modeling component estimates the population-level impact of a monthly formulation on HIV incidence relative to the current daily oral and injectable landscape.</p>
]]></description>
  <category>grant</category>
  <guid>https://samueljenness.org/news/2026-02-01-monthly-prep.html</guid>
  <pubDate>Sun, 01 Feb 2026 05:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Harrington): Social Network Analysis of University COVID-19 Contact Tracing</title>
  <link>https://samueljenness.org/news/2026-01-15-university-contact-tracing-sna.html</link>
  <description><![CDATA[
<p>New paper led by Kristin Harrington in <em>Public Health</em>: <strong>The Application of Social Network Analysis to Examine COVID-19 Contact Tracing Networks in a University Setting</strong>. This cohort study reconstructed contact networks from case investigation and contact tracing interviews during the Fall 2020 semester at a US university under hybrid learning. The analysis identified 441 COVID-19 cases, 1121 close contacts, and 1206 links, with a mean of 2.9 direct contacts per person. The overall secondary attack rate (SAR) was 9.7% (50/518), and contacts of symptomatic cases had a higher SAR than contacts of asymptomatic cases (11.8% versus 4.9%; p = 0.015). Networks were minimally clustered, suggesting that campus transmission may differ from other settings.</p>
<p><img src="https://samueljenness.org/img/papers/2026-01-15-university-contact-tracing-sna.jpg" alt="University COVID-19 contact tracing networks for November and December, with nodes shaded by case or contact status and cluster membership" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/41604913/">PubMed</a> · <a href="https://doi.org/10.1016/j.puhe.2026.106171">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2026-01-15-university-contact-tracing-sna.html</guid>
  <pubDate>Thu, 15 Jan 2026 05:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Nelson): Social Behavior for Infectious Disease in Four LMICs</title>
  <link>https://samueljenness.org/news/2025-10-15-social-lmics.html</link>
  <description><![CDATA[
<p>New paper led by Kristin Nelson in <em>Nature Communications</em>: <strong>Characterizing Social Behavior Relevant for Infectious Disease Transmission in Four Low- and Middle-Income Countries, 2021-2023</strong>. The population-based study collected two-day contact diaries from 5,085 participants in Guatemala, India, Mozambique, and Pakistan, yielding 84,829 contacts. Mean contact rates were highest among 10- to 19-year-olds in three countries and among 5- to 9-year-olds in Pakistan. Non-home locations with high transmission potential were schools in India, workplaces in Pakistan, and social or leisure settings in Mozambique and Guatemala. Among children under 5 years, contacts with non-household members were most common in Mozambique and least common in India, and age patterns diverged from projections based on high-income countries.</p>
<p><img src="https://samueljenness.org/img/papers/2025-10-15-social-lmics.jpg" alt="Mean daily contact rates by age in four low- and middle-income countries compared with POLYMOD-based projections" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/41168147/">PubMed</a> · <a href="https://doi.org/10.1038/s41467-025-64850-9">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2025-10-15-social-lmics.html</guid>
  <pubDate>Wed, 15 Oct 2025 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Jones): HealthMindr PrEP RCT</title>
  <link>https://samueljenness.org/news/2025-08-12-healthmindr.html</link>
  <description><![CDATA[
<p>New paper led by Jeb Jones in <em>JAIDS</em>: <strong>Randomized Controlled Trial of a HIV Prevention App to Increase Pre-exposure Prophylaxis Uptake among Gay and Bisexual Men Who Have Sex with Men in the United States: The HealthMindr PrEP Study</strong>. The trial randomized 658 gay and bisexual men who have sex with men in Ending the HIV Epidemic priority jurisdictions to the HealthMindr-PrEP app (437) or a control app (221), with follow-up over one year. Differences between arms in self-reported pre-exposure prophylaxis (PrEP) uptake were not statistically significant. Among participants with PrEP indications at baseline, the estimated rate of PrEP initiation was higher in the intervention arm, though the interval was consistent with no effect (hazard ratio 1.64, 95% CI 0.89 to 3.03); the estimate among those without indications was 1.05.</p>
<p><img src="https://samueljenness.org/img/papers/2025-08-12-healthmindr.jpg" alt="CONSORT flow diagram for the HealthMindr PrEP trial, showing allocation to the intervention and control apps and retention through 12 months of follow-up" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/40828543/">PubMed</a> · <a href="https://doi.org/10.1097/QAI.0000000000003747">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2025-08-12-healthmindr.html</guid>
  <pubDate>Tue, 12 Aug 2025 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Onwubiko): Optimizing HIV Partner Services among MSM Living with HIV</title>
  <link>https://samueljenness.org/news/2025-07-01-partner-services-plwh.html</link>
  <description><![CDATA[
<p>New paper led by Udodirim Onwubiko in <em>Sexually Transmitted Diseases</em>: <strong>Optimizing HIV Partner Services for Gay, Bisexual and Other Men Who Have Sex with Men Previously Diagnosed with HIV: A Modeling Study</strong>. Stochastic network models of HIV and bacterial sexually transmitted infection transmission in Atlanta tested two extensions of HIV partner services (HIV-PS). Expanding partner elicitation to partners of HIV-positive partners had minimal effect on HIV incidence, whereas adding people with previously diagnosed HIV who were out of care increased index-case and partner pools 10-fold. Prioritizing antiretroviral therapy (ART) reengagement for that group alongside optimized HIV-PS averted up to 63% of HIV infections relative to the base scenario in the model.</p>
<p><img src="https://samueljenness.org/img/papers/2025-07-01-partner-services-plwh.jpg" alt="Modeled relationship between index case and partner participation in HIV partner services and the percent of new HIV infections averted" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/40489800/">PubMed</a> · <a href="https://doi.org/10.1097/OLQ.0000000000002167">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2025-07-01-partner-services-plwh.html</guid>
  <pubDate>Tue, 01 Jul 2025 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Onwubiko): Depression at PrEP Initiation and PrEP Care Engagement</title>
  <link>https://samueljenness.org/news/2025-06-15-depression-prep-engagement.html</link>
  <description><![CDATA[
<p>New paper led by Udodirim Onwubiko in <em>JAIDS</em>: <strong>Impact of Depression at HIV PrEP Initiation on Sustained PrEP Care Engagement among US Gay and Bisexual Men</strong>. The study analyzed electronic health records for 8,077 gay and bisexual men prescribed oral preexposure prophylaxis (PrEP) at three Boston clinics between January 2015 and February 2022, each followed for 18 months. Baseline depression was diagnosed in 19% of the cohort. Over follow-up, 41% had prescription gaps, 38% dropped out, and 0.4% seroconverted without a prior gap. Depression was modestly associated with higher rates of prescription gaps (adjusted hazard ratio 1.10, 95% CI 1.00-1.20) and dropping out (1.16, 95% CI 1.05-1.28) relative to men without depression.</p>
<p><img src="https://samueljenness.org/img/papers/2025-06-15-depression-prep-engagement.jpg" alt="Trends in PrEP use disruptions among gay, bisexual, and other men who have sex with men prescribed oral PrEP" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/40373280/">PubMed</a> · <a href="https://doi.org/10.1097/QAI.0000000000003698">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2025-06-15-depression-prep-engagement.html</guid>
  <pubDate>Sun, 15 Jun 2025 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Violette): OTC HIV PrEP Support Among Transfeminine People</title>
  <link>https://samueljenness.org/news/2025-05-15-otc-prep-tf.html</link>
  <description><![CDATA[
<p>New paper led by Lauren Violette in <em>JAMA Network Open</em>: <strong>Support for Over-the-Counter HIV Preexposure Prophylaxis among Transfeminine People</strong>. The analysis drew on the 2023-2024 Transgender Women's Internet Survey and Testing study, an online cross-sectional survey of 1936 transgender women and transfeminine nonbinary people from all 50 states, 1684 of whom (87.0%) had never used preexposure prophylaxis (PrEP). Support for over-the-counter (OTC) PrEP availability was reported by 1677 respondents (86.6%), compared with 127 (6.6%) who did not support it and 114 (5.9%) who were unsure. Support was higher among respondents reporting 10 or more sex partners in the prior 12 months than among those reporting 0 to 1 (prevalence ratio 1.09, 95% CI 1.05-1.12).</p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/40833698/">PubMed</a> · <a href="https://doi.org/10.1001/jamanetworkopen.2025.27800">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2025-05-15-otc-prep-tf.html</guid>
  <pubDate>Thu, 15 May 2025 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Wallrafen-Sam): Responsive Vaccination Decisions and SARS-CoV-2 Spread</title>
  <link>https://samueljenness.org/news/2025-04-20-responsive-vaccination.html</link>
  <description><![CDATA[
<p>New paper led by Karina Wallrafen-Sam in <em>Epidemics</em>: <strong>Modelling the Interplay Between Responsive Individual Vaccination Decisions and the Spread of SARS-CoV-2</strong>. The study coupled a network- and agent-based model of SARS-CoV-2 transmission with a social-psychological decision-making model in which side effects and breakthrough infections nudged individuals toward vaccine resistance while spikes in COVID-19 hospitalizations nudged them toward willingness, calibrated to the epidemic in Georgia, USA from January 2021 to August 2022. In the model, raising the probability of hospitalization-prompted resistant-to-willing nudges increased vaccine uptake by as much as 5.4% and decreased SARS-CoV-2 incidence by as much as 4.0% relative to the calibrated baseline, whereas decreasing breakthrough-related willing-to-resistant nudges had negligible impact.</p>
<p><img src="https://samueljenness.org/img/papers/2025-04-20-responsive-vaccination.jpg" alt="Vaccines administered, incidence rate, and death rate across model scenarios varying the hospitalization nudge probability" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/40318563/">PubMed</a> · <a href="https://doi.org/10.1016/j.epidem.2025.100831">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2025-04-20-responsive-vaccination.html</guid>
  <pubDate>Sun, 20 Apr 2025 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Liu): COVID-19 Vaccination and Changes in Contact Patterns</title>
  <link>https://samueljenness.org/news/2025-04-01-covid-vaccination-contact.html</link>
  <description><![CDATA[
<p>New paper led by Carol Liu in <em>Epidemics</em>: <strong>The Effect of COVID-19 Vaccination on Change in Contact and Implications for Transmission</strong>. This analysis used a longitudinal cohort sampled from United States households that measured contact rates, risk mitigation, and COVID-19 vaccination status between August 2020 and April 2022. Contact rates increased across survey rounds in all sociodemographic groups, though unvaccinated participants reported persistently higher rates. In a multilevel generalized linear mixed effects model, individuals who newly completed a primary vaccine series reported an additional 1.93 contacts (95% CI 0.27 to 3.59) relative to those who remained unvaccinated. Transmission estimates from observed contact rates suggest these increases were not fully offset by vaccine protection against infection.</p>
<p><img src="https://samueljenness.org/img/papers/2025-04-01-covid-vaccination-contact.jpg" alt="Main effect estimates for contact change after vaccination and estimated relative transmission" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/40300469/">PubMed</a> · <a href="https://doi.org/10.1016/j.epidem.2025.100827">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2025-04-01-covid-vaccination-contact.html</guid>
  <pubDate>Tue, 01 Apr 2025 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Schneider): SARS-CoV-2 Prevention Interventions in Jails</title>
  <link>https://samueljenness.org/news/2025-02-15-jail-sarscov2-interventions.html</link>
  <description><![CDATA[
<p>New paper led by Isaac Schneider in <em>Infectious Disease Modelling</em>: <strong>Interventions for SARS-CoV-2 Prevention among Jailed Adults: A Network-Based Modeling Analysis</strong>. This analysis used a network-based SARS-CoV-2 transmission model parameterized with data from the Fulton County Jail in Georgia, representing contacts on cell and block network layers over 185 days with 300 simulations per scenario. Nine intervention scenarios combining vaccination, contact tracing with quarantine, and increased jail release were compared against a reference scenario without them. In the model, cell-level contact tracing alone averted 3.2% of infections relative to the reference scenario, while each other strategy averted over 10%; increased jail release averted nearly 20% of infections despite reducing the jail population by only 13%.</p>
<p><img src="https://samueljenness.org/img/papers/2025-02-15-jail-sarscov2-interventions.jpg" alt="Percentage of cell-level and block-level SARS-CoV-2 infections averted across 300 simulations for each of the nine intervention scenarios" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/40027595/">PubMed</a> · <a href="https://doi.org/10.1016/j.idm.2025.02.001">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2025-02-15-jail-sarscov2-interventions.html</guid>
  <pubDate>Sat, 15 Feb 2025 05:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Traeger): Real-World Doxy-PEP and Bacterial STIs</title>
  <link>https://samueljenness.org/news/2025-01-15-doxy-pep-realworld.html</link>
  <description><![CDATA[
<p>New paper led by Michael Traeger in <em>JAMA Internal Medicine</em>: <strong>Doxycycline Postexposure Prophylaxis and Bacterial Sexually Transmitted Infections among Individuals Using HIV Preexposure Prophylaxis</strong>. This retrospective cohort study analyzed electronic health record data from 11,551 adults dispensed HIV preexposure prophylaxis (PrEP) at Kaiser Permanente Northern California, of whom 2,253 (19.5%) received doxycycline postexposure prophylaxis (doxyPEP). Among doxyPEP recipients, quarterly chlamydia positivity fell from 9.6% before initiation to 2.0% after (rate ratio 0.21, 95% CI 0.16 to 0.27) and syphilis positivity from 1.7% to 0.3% (rate ratio 0.20, 95% CI 0.11 to 0.37); gonorrhea declined from 10.2% to 9.0% (rate ratio 0.88, 95% CI 0.77 to 1.00). Positivity remained stable among PrEP users not dispensed doxyPEP.</p>
<p><img src="https://samueljenness.org/img/papers/2025-01-15-doxy-pep-realworld.jpg" alt="Quarterly chlamydia, gonorrhea, and syphilis positivity from 24 months before to 12 months after starting doxycycline postexposure prophylaxis" /></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/39761062/">PubMed</a> · <a href="https://doi.org/10.1001/jamainternmed.2024.7186">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2025-01-15-doxy-pep-realworld.html</guid>
  <pubDate>Wed, 15 Jan 2025 05:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Jenness): Dynamic Contact Networks of Residents of an Urban Jail in the Era of SARS-CoV-2</title>
  <link>https://samueljenness.org/news/2024-11-15-jail-networks.html</link>
  <description><![CDATA[
<p>New paper in <em>Epidemics</em>: <strong>Dynamic Contact Networks of Residents of an Urban Jail in the Era of SARS-CoV-2</strong>.</p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/38776713/">PubMed</a> · <a href="https://doi.org/10.1016/j.epidem.2024.100772">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2024-11-15-jail-networks.html</guid>
  <pubDate>Fri, 15 Nov 2024 05:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Onwubiko): Sexual Stigma and Mental Distress in the PrEP Cascade</title>
  <link>https://samueljenness.org/news/2024-10-15-stigma-prep-cascade.html</link>
  <description><![CDATA[
<p>New paper led by Udodirim Onwubiko in <em>Social Science &amp; Medicine</em>: <strong>Individual and Joint Associations of Sexual Stigma and Mental Distress with PrEP Uptake, Adherence and Persistence among US Gay and Bisexual Men</strong>.</p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/39541830/">PubMed</a> · <a href="https://doi.org/10.1016/j.socscimed.2024.117493">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2024-10-15-stigma-prep-cascade.html</guid>
  <pubDate>Tue, 15 Oct 2024 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Onwubiko): Sexual Stigma, Poverty, and Mental Health among MSM</title>
  <link>https://samueljenness.org/news/2024-09-15-stigma-poverty-mental-health.html</link>
  <description><![CDATA[
<p>New paper led by Udodirim Onwubiko in <em>PLOS Mental Health</em>: <strong>Exploring the Intersections of Sexual Stigma, Poverty and Mental Health in HIV-Negative Gay, Bisexual and Other Men Who Have Sex with Men in the United States</strong>.</p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/41661778/">PubMed</a> · <a href="https://doi.org/10.1371/journal.pmen.0000212">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2024-09-15-stigma-poverty-mental-health.html</guid>
  <pubDate>Sun, 15 Sep 2024 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New paper (Harrington): COVID-19 Lockdowns and Drug-Resistant TB in KwaZulu-Natal</title>
  <link>https://samueljenness.org/news/2024-08-01-covid-lockdowns-tb.html</link>
  <description><![CDATA[
<p>New paper led by Kristin Harrington in <em>Annals of Epidemiology</em>: <strong>The Impact of COVID-19 National Lockdowns on Drug-Resistant Tuberculosis in KwaZulu-Natal, South Africa: A Spatial Analysis</strong>.</p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/39038747/">PubMed</a> · <a href="https://doi.org/10.1016/j.annepidem.2024.07.044">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2024-08-01-covid-lockdowns-tb.html</guid>
  <pubDate>Thu, 01 Aug 2024 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New R01 funded: SILOS</title>
  <link>https://samueljenness.org/news/2024-07-01-silos.html</link>
  <description><![CDATA[
<p>Received Site PI role on the new <em>NIH</em>-funded <strong>SILOS: Structural Inequities across Layers of Social-Context as Drivers of HIV and Substance Use</strong> (<a href="https://reporter.nih.gov/">R01 DA061247</a>), studying social and structural factors in HIV transmission and substance use among young MSM and transgender women.</p>
]]></description>
  <category>grant</category>
  <guid>https://samueljenness.org/news/2024-07-01-silos.html</guid>
  <pubDate>Mon, 01 Jul 2024 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New R21 funded: OFFSCRIPT (Over-the-Counter PrEP)</title>
  <link>https://samueljenness.org/news/2024-05-15-offscript.html</link>
  <description><![CDATA[
<p>Received Site PI role on the new <em>NIH</em>-funded <strong>Over-the-Counter PrEP: Acceptability, Feasibility, and Potential Impact of Access Without a Prescription</strong> (<a href="https://reporter.nih.gov/">R21 MH136855</a>). Evaluates the feasibility and impact of removing the need for a PrEP prescription.</p>
]]></description>
  <category>grant</category>
  <guid>https://samueljenness.org/news/2024-05-15-offscript.html</guid>
  <pubDate>Wed, 15 May 2024 04:00:00 GMT</pubDate>
</item>
<item>
  <title>New methods paper: Extending STERGM Approximations</title>
  <link>https://samueljenness.org/news/2024-03-01-stergm-approximations.html</link>
  <description><![CDATA[
<p>New methods paper in the <em>Journal of Computational and Graphical Statistics</em>: <strong>Improving and Extending STERGM Approximations Based on Cross-Sectional Data and Tie Durations</strong>. Methods that underpin efficient dynamic-network simulation in EpiModel.</p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/38455738/">PubMed</a> · <a href="https://doi.org/10.1080/10618600.2023.2233593">DOI</a></p>
]]></description>
  <category>paper</category>
  <guid>https://samueljenness.org/news/2024-03-01-stergm-approximations.html</guid>
  <pubDate>Fri, 01 Mar 2024 05:00:00 GMT</pubDate>
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